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Funding Type:
Grant Funding
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Opportunity From:
The National Institutes of Health (NIH) National Institute on Aging (NIA)
Important Dates:
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Letter of Intent (LOI) Deadline:
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September 06, 2024
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Application Deadline:
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October 07, 2024
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Opportunity Description:
This Notice of Funding Opportunity (NOFO) invites applications proposing innovative strategies to target and manipulate brain cell subtypes that are altered in aging, Alzheimer's Disease (AD), and AD-Related Dementias (ADRDs). ADRDs include frontotemporal disorders (FTD), Lewy body dementia (LBD), vascular contributions to cognitive impairment and dementia (VCID), and multiple etiology dementias (MED). Specifically, the goal of this NOFO is to encourage the development and utilization of sophisticated tools that pair breakthroughs in adeno-associated virus (AAV) capsid engineering with enhancer element identification to do the following:
1. Optimize precise targeting of disease-relevant cell subtypes in aged and degenerating mammalian brains.
2. Monitor and/or manipulate these cells in vivo to address mechanistic hypotheses related to brain aging and AD/ADRD in animal models.
Application Due Date:
October 07, 2024
Contact:
Erin E. Gray, Ph.D.
Division of Neuroscience
National Institute on Aging (NIA)
Telephone: 301-451-3968
Email: erin.gray@nih.gov